Ewing's Sarcoma Treatment by Stage

One of the most important factors affecting Ewing's sarcoma treatment is whether the tumor is classified as localized, metastatic, or recurrent. In general, Ewing's sarcoma treatment can include surgery, radiation therapy, and chemotherapy. Rather than describe Ewing's sarcoma treatment by stage, the following article describes treatment of the disease based on how cases of the cancer are classified.

 

Ewing's Sarcoma Treatment by Stage: An Overview

Ewing's sarcoma treatment options vary based on:
 
  • Whether the tumor is localized, metastatic, or recurrent (see Ewing's Sarcoma Stages)
  • Where the tumor is located
  • The patient's age and general health.
     
In general, Ewing's sarcoma treatment options can include:
 
  • Surgery
  • Radiation therapy
  • Chemotherapy.
     
Rather than using a staging system, most cases of Ewing's sarcoma are classified as being either:
 
  • Localized
  • Metastatic
  • Recurrent.
     

Treatment for Localized Ewing's Sarcoma

Treatment for localized Ewing's sarcoma may include:
 
  • A clinical trial of chemotherapy followed by radiation therapy
  • Combination chemotherapy followed by surgery, with or without radiation therapy
  • A clinical trial of intensified chemotherapy
  • A clinical trial of post-surgical chemotherapy with or without stem cell transplant.
     

Treatment for Metastatic Ewing's Sarcoma

Treatment for metastatic Ewing's sarcoma may include:
 
  • Combination chemotherapy followed by radiation therapy, surgery, or both 
  • High-dose chemotherapy (with or without radiation therapy), plus additional stem cell support
  • A clinical trial of intensive chemotherapy with multiple chemotherapy drug combinations.
     
(Ewing's Sarcoma Treatment by Stage Continued: Page 2)
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Written by/reviewed by: Arthur Schoenstadt, MD
Last reviewed by: Arthur Schoenstadt, MD