Bone Cancer Home > Malignant Fibrous Histiocytoma Information

A rare condition, malignant fibrous histiocytoma is characterized by a tumor of the bone or soft tissues. In many cases, the tumor appears in the legs or arms, but it can also develop in other parts of the body. Malignant fibrous histiocytoma is the most common soft tissue cancer diagnosed in older adults -- it is often diagnosed in people between the ages of 50 and 70.
Symptoms of this condition will vary from person to person, based on the size and location of the tumor. Besides an enlarging painless mass, other common symptoms include fractures (when the disease affects bone), fever, weight loss, and low blood sugar.
Surgery and chemotherapy are two of the most commonly used treatments for malignant fibrous histiocytoma.
(For more information on this topic, including a list of tests that may be used to confirm a diagnosis, click Malignant Fibrous Histiocytoma.)
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Last reviewed by: Arthur Schoenstadt, MD
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