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Malignant Fibrous Histiocytoma

How Is It Diagnosed?

If a doctor suspects malignant fibrous histiocytoma, he or she will likely need to perform a physical exam, ask about the patient's personal and family medical history, and recommend additional tests and procedures. Procedures and tests that healthcare providers use to make a diagnosis include:
  • X-rays
  • Computed tomography (CT) scan
  • Magnetic resonance imaging (MRI) scan
  • Bone scan
  • Biopsy.

Malignant Fibrous Histiocytoma Staging

Once healthcare providers make a malignant fibrous histiocytoma diagnosis, they may order more tests to find out if cancer cells have spread to other parts of the body. This is called staging.
Currently, there is no staging system for the different types of malignant fibrous histiocytoma. Instead, most patients are grouped depending on whether the disease is found in only one part of the body (localized) or whether it has spread from one part of the body to another (metastasized).
The doctor will need to determine where the cancer is located and how far the disease has spread in order to plan the best treatment.

Treatment Options

Malignant fibrous histiocytoma is generally treated the same as osteosarcoma and appears to have a similar response to treatment. Options vary, based on factors such as:
  • Whether the malignant fibrous histiocytoma is localized or metastatic
  • Where the tumor is found
  • The patient's age and general health.
In general, malignant fibrous histiocytoma treatment options include surgery and chemotherapy. Patients should work with their doctors to develop a treatment plan that meets their medical needs and personal values. Choosing the most appropriate methods is a decision that ideally involves the patient, the family, and the healthcare team.
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Malignant Fibrous Histiocytoma Information

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