No one knows the exact cause or causes of
osteosarcoma; however, research has shown that people with certain risk factors are more likely than others to develop osteosarcoma. A risk factor is anything that increases a person's chances of developing a disease.
Specific risk factors for osteosarcoma include:
- Being a child or young adult
- Having undergone radiation therapy or chemotherapy
- Having a history of Paget's disease
- Having a family history of osteosarcoma
- Having hereditary retinoblastoma.
